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University of Adelaide and Holocyte collaborate on National Industry PhD project

 NIPhD Regional Director David Beecham, is thrilled to announce University of Adelaide’s collaboration with Holocyte on an Australian Government Department of Education National Industry PhD project aimed at tackling key challenges in the purification sector! PhD Candidate Manuella Cazelato Pires, under the supervision of Lukas Gerstweiler and Tocvic Xiangqian Meng will undertake an intellectually stimulating project that aims to deliver practical solutions to real industrial challenges, making a tangible positive impact.

Project Overview: The project focuses on developing green, safe, and cost-effective polysaccharide-based matrices for next-generation protein and macromolecule purification. This innovative material is expected to offer higher resolutions and productivities compared to traditional matrixes, revolutionising protein science and fine chemistry. Additionally, it has the potential to create value in the mineral and medical sectors, such as in industrial gas and mineral separation processes and therapeutic devices.

Collaborative Approach: By combining the University of Adelaide‘s renowned expertise in bioprocessing and cutting-edge laboratories with Holocyte‘s industry leadership in polysaccharide-based high-performance materials, this project is set to drive groundbreaking discoveries in the field. 

Value for Industry: Holocyte anticipate that this research will lead to the creation of innovative purification media that can effectively address persistent industry challenges. By collaborating with the University of Adelaide, we can investigate this topic in-depth and develop new high-performance materials. The expected outcomes can also lead to novel materials used in medical devices, mining, and gas refinement.

Value for Academia: This project will not only advance the field of purification sciences but also strengthen the University of Adelaide‘s position as a leading bioprocess research hub. 

Student Perspective: PhD candidate Manuella Cazelato Pires, with a background in protein purification, is excited to deepen her knowledge in this subject. Manuella hopes that the outcomes of her research can help reduce the cost of manufacturing biopharmaceuticals and other chemicals, ultimately having a positive impact on society.

Project Milestones:
Manufacturing high-strength polysaccharide-based porous materials with a defined pore structure; chemical modification of the materials to allow for defined adsorption behavior and; investigating the performance of these novel materials on the purification performance of a variety of molecules. 

Thanks to Mark Neuendorf at the University of Adelaide for coordinating the application and a successful kick off meeting.

For more information regarding the National Industry PhD Program, please visit: https://lnkd.in/gpVsGZZ6

 

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